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Michael Z. Lin, MD, PhD

Michael Z. Lin, MD, PhD

Project title
"Building the magic bullet: protein switches for sensing oncogenic signals and executing therapeutic programs"

Currently available cancer treatments, such as chemotherapeutics, targeted inhibitors or immunotherapies, are not capable of fully eradicating cancers and are limited by toxicities and side effects. 

Dr. Lin aims to take a new approach to cancer treatment by engineering a virus that will infect and replicate specifically in cancer cells, triggering their destruction. This strategy aims not to suppress oncogenic signaling, but to use it as a trigger for a smart biological therapy. If he succeeds, progress will be made toward developing a much-needed "magic bullet" against cancer.

 

Institution
Stanford University School of Medicine
Cancer type
Breast
Colorectal
Research area
Signal Transduction
Award Program
Innovator