Matthew P. Miller, PhD

Dr. Miller [HHMI Fellow] is investigating how cells ensure the correct partitioning of genetic material during cell division. Errors in this process occur in nearly all tumor cells and are the leading cause of miscarriages and congenital birth defects in humans. He is using novel techniques to isolate and examine the physical binding properties of the molecules that mediate this process. The goal of his work is to determine the molecular mechanisms that direct genome partitioning during cell division and understand how this process occurs with a high level of fidelity in normal cells, yet is error-prone during tumorigenesis.