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Liron Bar-Peled, PhD

Liron Bar-Peled, PhD

Project title
"Identification of cysteine liabilities in NRF2-driven cancers"

Dr. Bar-Peled studies how cancer cells adapt to stress environments, focusing on oxidative stress.  His research focuses on understanding how cells sense and respond to specific changes in their environment by activating singling pathways that lead to uncontrolled growth.  He recently studied a particular pathway in non-small cell lung cancer and identified a “druggable” protein that could be targeted with small molecules and disrupt this uncontrolled growth. He plans to pursue this specific target and use the same strategy for identifying druggable pathways in other cancers that currently lack effective therapies.

Institution
Massachusetts General Hospital
Cancer type
All Cancers
Research area
Chemical Biology
Award Program
Dale Frey Scientist