Skip to main content

Daniel H. Lin, PhD

Daniel H. Lin, PhD

Project title
"The influence of RNA and protein conformation on target-directed miRNA degradation"

Dr. Lin [HHMI Fellow] is studying how small RNAs called miRNAs are specifically targeted for destruction in cells. Because miRNAs are key regulators of gene expression, both miRNA production and destruction must be controlled in an accurate and timely manner. Dysregulation of these processes contributes to cancer progression. Dr. Lin is developing biochemical and high-throughput sequencing approaches to uncover the rules governing miRNA destruction and how they change in cancer.

Institution
Whitehead Institute for Biomedical Research
Sponsor(s) / Mentor(s)
David P. Bartel, PhD
Cancer type
All Cancers
Research area
RNA (RNA processing, miRNA and piRNA mechanisms, enzymatic RNAs, etc.)
Award Program
Fellow
Named Award
HHMI Fellow