Skip to main content

Rodrigo Gier, PhD

Rodrigo Gier, PhD

Project title
"Targeted chemical aggregation as a general strategy to overcome cancer drug resistance"

Drug therapies that selectively target proteins that drive the growth of tumor cells are rapidly becoming the standard of care for many cancers. However, tumors are often able to evade inhibition by targeted anti-cancer drugs by activating other proteins, leading to drug resistance. Dr. Gier [HHMI Fellow] is developing a new therapeutic approach that repurposes existing drugs to release highly toxic cargoes, known as payloads, that aggregate in drug-resistant cancer cells and kill them. As a general platform, it is applicable to a wide range of solid and liquid cancers. Dr. Gier received his PhD from University of Pennsylvania, Philadelphia and his BA from Swarthmore College, Swarthmore. 

Institution
University of California, San Francisco
Sponsor(s) / Mentor(s)
Kevan M. Shokat, PhD
Cancer type
Blood
Other Cancer
Lung
Research area
Chemical Biology
Award Program
Fellow
Named Award
HHMI Fellow