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Challice L. Bonifant, MD, PhD

Challice L. Bonifant, MD, PhD

Project title
"Dual-antigen targeting by ENG-T cells as improved anti-AML therapy"

Dr. Bonifant is studying how best to direct the immune system to combat acute myeloid leukemia (AML), a blood cancer of both children and adults. By specifically directing T immune cells to AML, she hopes to make therapy stronger and more effective, while also reducing toxicity. She is exploring the activity of T cells targeting multiple AML-specific antigens that do not affect normal cells. The ultimate goal of the work is to develop new strategies to treat AML.

Institution
The Johns Hopkins University School of Medicine
Sponsor(s) / Mentor(s)
Donald Small, MD, PhD
Cancer type
Blood
Pediatric
All Cancers
Research area
Immunotherapy
Award Program
Sohn Fellow