Dr. Wang is applying a chemical biology approach to identify kinases and small molecule inhibitors that enhance the immune system’s tumor surveillance capabilities. Therapies that enhance the anti-tumor activity of the immune system have shown tremendous promise in patients; however, only a subset of patients and tumors respond well to such treatments, so identifying complementary strategies to increase the effectiveness of existing immunotherapies is increasingly important. His goal is to obtain mechanistic insight into the anti-tumor immune response and to identify small molecule drugs that may improve the efficacy of immunotherapies in patients.